Gut microbiome regulation

ftf-blue-hiRes

Principal Investigator

Jia-Sheng Wang, Professor and Head, Department of Environmental Health Science,
University of Georgia, Room 206A, 150 East Green Street, Athens, GA 30602;
jswang@uga.edu

Co-PIs:

Lili Tang, Associate Professor, Department of Environmental Health Science,
University of Georgia, Room 142, 150 East Green Street, Athens, GA 30602;
ltang@uga.edu

John Ssempebwa, Senior lecturer, Department of Disease Control and Environmental Health, Makerere University School of Public Health, Kampala, Uganda;
jssems@musph.ac.ug




Regulation of gut microbiome by peanut supplement in youth

Area of Inquiry: Nutrition

Country focus: Uganda

Project length: 3 years

Budget: $500,000

Gut microbiota are considered critical to human health and immunity. Their functions range from the regulation of host nutrition and nutrient metabolism to therapeutic roles in many types of human diseases, including disorders in the growth and development of youth. This project studies the effects of peanut consumption on the gut microbiota of Ugandan youth. Next-generation sequencing and high-throughput analytical techniques is used to perform metagenomics and metabolomics analyses to assess the regulatory effects of peanuts consumption on the structure and function of gut microbiome. The project will also explore the differences on growth parameters between youth who regularly consume peanuts versus those who rarely consume peanut/peanut-based meals, as well as variations of the peanut effects between girls and boys.